The severity of nosocomial infection has increased with following problem, e.g., complexity of hospital, antibiotic abuse, use of immunosuppressive agent, increment of chronic diseases, multiplicity of operations. From this situation, we analysed 6, 415 surgical patients admitted and operated during 1980 and 1982 when our new hospital was built and every fitted condition was made. The results were as follows.:
1) The nosocomial infection rate was decreased by year. It was 8.64% in 1980, then, 5.27% in 3.52% in 1982.
2) The infection rates related to the various degrees of contamination showed 1.2% for the clean, 4.5% for the clean contaminated, 24.4% for the contaminated and 47.6% for the dirty wound.
The infection rate of the clean wound was remarkably decreased by year.: 1.9% in 1980, 1.29% in 1981, 0.53% in 1982.
3) Skin wound infection was the most frequent and its rate was 56.9%, then gastrointestinal and intraperitoneal, respiratory tract infection, bacteremia and urinary tract infection in descending order.
4) The bacteria cultured frequently were E. coli, Kiebsiella spp, Proteus spp, and Enterobacter spp.
The gram negative bacteria were three times as much cultured as the gram positive bacteria.
5) In this analysis, the risk factors of nosocomial infection were duration of preoperative hospitalization, age, nutrition, urinary catheterization etc.
In conclusion, interhospital multidisciplinary effort should be needed for the prevention of nosocomial infection.
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